Review





Similar Products

mpc 11 mouse tumors  (ATCC)
96
ATCC mpc 11 mouse tumors
Mpc 11 Mouse Tumors, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mpc 11 mouse tumors/product/ATCC
Average 96 stars, based on 1 article reviews
mpc 11 mouse tumors - by Bioz Stars, 2026-04
96/100 stars
  Buy from Supplier
mpc-385  (AutoMate Scientific Inc)
96
AutoMate Scientific Inc mpc-385
Mpc 385, supplied by AutoMate Scientific Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mpc-385/product/AutoMate Scientific Inc
Average 96 stars, based on 1 article reviews
mpc-385 - by Bioz Stars, 2026-04
96/100 stars
  Buy from Supplier
igg2b isotype control antibody  (ATCC)
96
ATCC igg2b isotype control antibody
The Role of CD4 + T Cells in Cardiac Functional Remodeling (A) Experimental design. (B and C) Flow cytometric analysis of CD4 + T cells in peripheral blood of TCRM mice treated with <t>IgG2b</t> isotype control or anti-CD4 antibody. (D) Representative H&E and PSR-stained heart sections. (E) Myocarditis score and (F) quantification of PSR-positive area, in 8-week-old TCRM mice subjected to the indicated treatment. (G to J) Echocardiographic assessment of left ventricular morphology and function in 8-week-old TCRM mice treated with isotype control or anti-CD4 antibody. (G) LVID systole, (H) LVEF, (I) GCS, (J) GLS. (C, E to J) Pooled data from 3 independent experiments, including n = 12 anti-CD4-treated TCRM mice and n = 13 isotype-treated TCRM mice of which n = 5 progressed to iCMP. Statistical analysis was performed using C, unpaired 2-tailed Student’s t -test or Mann-Whitney U test and (E to J) 1-way analysis of variance with Tukey’s post hoc test or Kruskal-Wallis test with Dunnett’s multiple comparisons test. Boxplots as in . ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001. Abbreviations as in and .
Igg2b Isotype Control Antibody, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/igg2b isotype control antibody/product/ATCC
Average 96 stars, based on 1 article reviews
igg2b isotype control antibody - by Bioz Stars, 2026-04
96/100 stars
  Buy from Supplier
ccl 86 mpc 5 podocyte cell line peter mundel  (ATCC)
99
ATCC ccl 86 mpc 5 podocyte cell line peter mundel
The Role of CD4 + T Cells in Cardiac Functional Remodeling (A) Experimental design. (B and C) Flow cytometric analysis of CD4 + T cells in peripheral blood of TCRM mice treated with <t>IgG2b</t> isotype control or anti-CD4 antibody. (D) Representative H&E and PSR-stained heart sections. (E) Myocarditis score and (F) quantification of PSR-positive area, in 8-week-old TCRM mice subjected to the indicated treatment. (G to J) Echocardiographic assessment of left ventricular morphology and function in 8-week-old TCRM mice treated with isotype control or anti-CD4 antibody. (G) LVID systole, (H) LVEF, (I) GCS, (J) GLS. (C, E to J) Pooled data from 3 independent experiments, including n = 12 anti-CD4-treated TCRM mice and n = 13 isotype-treated TCRM mice of which n = 5 progressed to iCMP. Statistical analysis was performed using C, unpaired 2-tailed Student’s t -test or Mann-Whitney U test and (E to J) 1-way analysis of variance with Tukey’s post hoc test or Kruskal-Wallis test with Dunnett’s multiple comparisons test. Boxplots as in . ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001. Abbreviations as in and .
Ccl 86 Mpc 5 Podocyte Cell Line Peter Mundel, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ccl 86 mpc 5 podocyte cell line peter mundel/product/ATCC
Average 99 stars, based on 1 article reviews
ccl 86 mpc 5 podocyte cell line peter mundel - by Bioz Stars, 2026-04
99/100 stars
  Buy from Supplier

Image Search Results


The Role of CD4 + T Cells in Cardiac Functional Remodeling (A) Experimental design. (B and C) Flow cytometric analysis of CD4 + T cells in peripheral blood of TCRM mice treated with IgG2b isotype control or anti-CD4 antibody. (D) Representative H&E and PSR-stained heart sections. (E) Myocarditis score and (F) quantification of PSR-positive area, in 8-week-old TCRM mice subjected to the indicated treatment. (G to J) Echocardiographic assessment of left ventricular morphology and function in 8-week-old TCRM mice treated with isotype control or anti-CD4 antibody. (G) LVID systole, (H) LVEF, (I) GCS, (J) GLS. (C, E to J) Pooled data from 3 independent experiments, including n = 12 anti-CD4-treated TCRM mice and n = 13 isotype-treated TCRM mice of which n = 5 progressed to iCMP. Statistical analysis was performed using C, unpaired 2-tailed Student’s t -test or Mann-Whitney U test and (E to J) 1-way analysis of variance with Tukey’s post hoc test or Kruskal-Wallis test with Dunnett’s multiple comparisons test. Boxplots as in . ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001. Abbreviations as in and .

Journal: JACC: Basic to Translational Science

Article Title: Cardiopathogenic T Cells Govern Progression and Functional Remodeling in Inflammatory Cardiomyopathy and Chronic Myocarditis

doi: 10.1016/j.jacbts.2025.101458

Figure Lengend Snippet: The Role of CD4 + T Cells in Cardiac Functional Remodeling (A) Experimental design. (B and C) Flow cytometric analysis of CD4 + T cells in peripheral blood of TCRM mice treated with IgG2b isotype control or anti-CD4 antibody. (D) Representative H&E and PSR-stained heart sections. (E) Myocarditis score and (F) quantification of PSR-positive area, in 8-week-old TCRM mice subjected to the indicated treatment. (G to J) Echocardiographic assessment of left ventricular morphology and function in 8-week-old TCRM mice treated with isotype control or anti-CD4 antibody. (G) LVID systole, (H) LVEF, (I) GCS, (J) GLS. (C, E to J) Pooled data from 3 independent experiments, including n = 12 anti-CD4-treated TCRM mice and n = 13 isotype-treated TCRM mice of which n = 5 progressed to iCMP. Statistical analysis was performed using C, unpaired 2-tailed Student’s t -test or Mann-Whitney U test and (E to J) 1-way analysis of variance with Tukey’s post hoc test or Kruskal-Wallis test with Dunnett’s multiple comparisons test. Boxplots as in . ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001. Abbreviations as in and .

Article Snippet: Mice were treated with 500 μg of anti-CD4 antibody (clone: YTS191, ECACC, 87072282) or IgG2b isotype control antibody (clone: MPC-11, ECACC, ATCC CCL-167) by intraperitoneal injection twice a week as demonstrated in the respective experiments.

Techniques: Functional Assay, Control, Staining, MANN-WHITNEY